Cerebral vasomotor reactivity to postural change is impaired in patients with cerebrovascular white matter lesions
نویسندگان
چکیده
منابع مشابه
Impaired cerebrovascular hemodynamics are associated with cerebral white matter damage.
White matter hyperintensities (WMH) in elderly individuals with vascular diseases are presumed to be due to ischemic small vessel diseases; however, their etiology is unknown. We examined the cross-sectional relationship between cerebrovascular hemodynamics and white matter structural integrity in elderly individuals with vascular risk factors. White matter hyperintensity volumes, fractional an...
متن کاملImpaired cerebrovascular reactivity with steal phenomenon is associated with increased diffusion in white matter of patients with Moyamoya disease.
BACKGROUND AND PURPOSE Reduced cerebrovascular reactivity (CVR) with steal phenomenon is an independent predictor for stroke and may indicate tissue exposed to episodic low-grade ischemia. The apparent diffusion coefficient (ADC) calculated using diffusion-weighted MRI is effective in characterizing focal brain ischemia and subtle structural changes in normal-appearing white matter (WM). We hyp...
متن کاملCerebrovascular reactivity is impaired in patients with cardiac failure.
AIMS We undertook this study to evaluate potential changes in cerebral vasoreactivity in patients with cardiac failure and their consequent dependence upon cardiac functional variables. METHODS AND RESULTS A total of 50 patients with various degrees of heart failure, 20 age-matched controls and 20 normal controls were examined. Cerebrovascular reactivity was examined with the carbon dioxide t...
متن کاملCerebral vasomotor reactivity and extent of white matter lesions in middle-aged men with arterial hypertension: a pilot study.
BACKGROUND Cerebrovascular reactivity (CVR) impairment and cerebral white matter lesions (WMLs) are associated in elderly or patients with overt cerebral ischemia. Such association has not been confirmed for asymptomatic middle-aged individuals with risk factors for stroke. We assessed the relationship between the CVR and the presence of WMLs in a middle-aged population-based cohort of hyperten...
متن کاملCerebrovascular reactivity and white matter integrity.
OBJECTIVE To compare the diffusion and perfusion MRI metrics of normal-appearing white matter (NAWM) with and without impaired cerebrovascular reactivity (CVR). METHODS Seventy-five participants with moderate to severe leukoaraiosis underwent blood oxygen level-dependent CVR mapping using a 3T MRI system with precise carbon dioxide stimulus manipulation. Several MRI metrics were statistically...
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ژورنال
عنوان ژورنال: Journal of Neurology
سال: 2003
ISSN: 0340-5354,1432-1459
DOI: 10.1007/s00415-003-0996-1